COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths

Abstract Objectives: to describe epidemiological characteristics and deaths in children with cancer COVID-19 at a reference hospital Recife, Brazil. Methods: cohort involving under the age of 19 underwent treatment during April July 2020. During pandemic, real-time reverse transcriptase polymerase chain reaction assay (RT-PCR) for severe acute respiratory syndrome coronavirus 2 (SARS -CoV-2) nasal / oropharyngeal swab were collected symptomatic patients or before hospitalization. Those detectable results included this study. The outcomes delayed on death. Descriptive analysis was performed presented preliminary results. Results: 48 participated cohort, mostly hematological neoplasms (66.6%.),69% male, median 5.5 years. most frequent symptoms fever (58.3%) coughing (27.7%);72.9% required hospitalization, 20% had support ICU 10.5% invasive ventilatory assistance.66.6% their oncological postponed, 16.6% died within 60 days after confirmation SARS-CoV-2 infection. Conclusions: led delay higher mortality frequency when compared historical series service. It would be important analyze risk factors determine survival impact.